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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
43.64
Human Site:
T214
Identified Species:
68.57
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
T214
V
Y
R
A
G
I
A
T
H
F
V
D
S
E
K
Chimpanzee
Pan troglodytes
XP_515988
440
48807
T268
V
Y
R
A
G
I
A
T
H
F
V
D
S
E
K
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
T272
V
Y
R
A
G
I
A
T
H
F
V
D
S
E
K
Dog
Lupus familis
XP_848689
359
39946
D196
F
V
D
S
E
K
L
D
M
L
E
E
D
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
T213
V
H
R
A
G
I
A
T
H
F
V
D
S
E
K
Rat
Rattus norvegicus
Q5XIE6
385
43006
T213
V
H
R
A
G
I
A
T
H
F
V
D
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
T213
V
L
K
A
G
I
A
T
H
F
V
E
S
G
K
Frog
Xenopus laevis
A2VDC2
385
42348
T213
V
Q
K
A
G
I
A
T
H
F
V
E
S
E
K
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
T210
V
Q
R
V
G
V
A
T
H
F
V
Q
S
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
T218
V
Y
Y
S
G
I
A
T
H
Y
C
E
S
S
K
Honey Bee
Apis mellifera
XP_396249
396
44074
T219
V
L
L
A
G
I
A
T
H
F
V
P
S
E
K
Nematode Worm
Caenorhab. elegans
P34559
288
31153
K125
W
T
A
V
S
D
V
K
K
P
V
I
A
A
V
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
T207
V
L
H
A
G
V
A
T
H
F
V
E
A
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
T211
S
N
Q
T
F
I
S
T
I
L
D
A
Y
A
E
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
Y217
V
V
T
G
A
D
A
Y
M
L
G
L
A
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
0
N.A.
93.3
93.3
N.A.
N.A.
73.3
80
73.3
N.A.
60
80
6.6
60
P-Site Similarity:
100
100
100
13.3
N.A.
100
100
N.A.
N.A.
86.6
93.3
80
N.A.
80
80
13.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
60
7
0
80
0
0
0
0
7
20
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
7
0
0
14
0
7
0
0
7
34
7
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
7
34
0
54
7
% E
% Phe:
7
0
0
0
7
0
0
0
0
67
0
0
0
0
0
% F
% Gly:
0
0
0
7
74
0
0
0
0
0
7
0
0
7
0
% G
% His:
0
14
7
0
0
0
0
0
74
0
0
0
0
0
7
% H
% Ile:
0
0
0
0
0
67
0
0
7
0
0
7
0
0
0
% I
% Lys:
0
0
14
0
0
7
0
7
7
0
0
0
0
0
74
% K
% Leu:
0
20
7
0
0
0
7
0
0
20
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% P
% Gln:
0
14
7
0
0
0
0
0
0
0
0
7
0
7
0
% Q
% Arg:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
14
7
0
7
0
0
0
0
0
67
14
0
% S
% Thr:
0
7
7
7
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
80
14
0
14
0
14
7
0
0
0
74
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
27
7
0
0
0
0
7
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _